Robert gill california emerging infections program

Geographic limitations in babesiosis are virtually erased by the mobility of donors and blood products. The blood bank involved in this case has blood collection centers in California and Maine but provides blood products to hospitals throughout southern California and the East Coast. Medical evaluation for babesiosis in both febrile and afebrile transfusion patients should include a Giemsa-stained thin blood smear, an acute serologic evaluation by IFA testing and a convalescent serologic evaluation by IFA testing taken 4—6 weeks apart 9 , and PCR evaluation of whole blood.

The varied clinical spectrum of babesiosis makes its detection in blood donors challenging. This case exemplifies the limitations in screening healthy asymptomatic donors for babesiosis. Available screening tests to detect Babesia spp. Nucleic acid testing and inactivation procedures may provide useful options for detecting Babesia spp. Until effective screening procedures are available, however, diagnosis of babesiosis in blood donors will continue to be based primarily on clinical observation.

Ms Ngo is an epidemiologist and Dr Civen is a medical epidemiologist. Their research interests include the surveillance and epidemiology of vector-borne diseases affecting Los Angeles County. We thank Robert Hunter for coordinating the blood bank investigation, Anne Kjemtrump and Barbara Herwaldt for their expertise and advice in the clinical and epidemiological aspects of babesiosis, Marianna Wilson and David E. Dassey for their thoughtful review, and the laboratory staff at CDC for their assistance with testing and confirmation.

Table of Contents — Volume 15, Number 5—May Please use the form below to submit correspondence to the authors or contact them at the following address:.

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The score is derived from an automated algorithm, and represents a weighted count of the amount of attention Altmetric picked up for a research output. Section Navigation. Facebook Twitter LinkedIn Syndicate. Article Metrics. Van Ngo and Rachel Civen. Abstract Babesiosis was reported in a California resident who received a transfusion of blood products collected in the disease-endemic northeastern region of the United States.

The Case. Leiby DA. Babesiosis and blood transfusion: flying under the radar. Vox Sang. Apicomplexa: Babesiidae from humans and its differentiation from other piroplasms. Int J Parasitol. Emerg Infect Dis. PubMed Google Scholar. Maine Center for Disease Control and Prevention.

Reportable infectious diseases in Maine, Summary [cited May 20]. Rhode Island Department of Health. Health topics: babesiosis [cited May 20]. Transmission of tick-borne agents of disease by blood transfusion: a review of known and potential risks in the United States. N Engl J Med. Clin Infect Dis. Investigation of transfusion transmission of a WA1-type babesial parasite to a premature infant in California. Yao J. Infections transmitted from use of blood products. Articles by Country Search — Search articles by the topic country.

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